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Proteins and Peptides

LL 37 (human) biotinylated, pegylated

Product Sizes
1 mg
AM-200-1MG
Academic Pricing
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About this Product
SKU:
AM-200
Additional Names:
Biotin-[PEG(4)]-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES-OH, LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES, LL 37 (human) biotinylated, pegylated is the N-terminally biotinylated, biotin, pegylated chain, PEG(4), antimicrobial, antitumour, antiviral, immunomodulatory, chemotaxis, angiogenesis, LL37, AM-200, AM200, LL-37
Conjugate:
Biotin
Extra Details:
LL 37 (human) biotinylated, pegylated is the N-terminally biotinylated version of the host defence peptide LL 37 with a biotin group attached via a pegylated chain, PEG(4). The presence of the biotin tag allows numerous biochemical and microbiological applications. LL 37, derived from the C-terminal of human cathelicidin antimicrobial peptide (CAMP, hCAP18), has antimicrobial, antitumour, antiviral and immunomodulatory properties and also has physiological functions in chemotaxis, promotion of wound closure, and angiogenesis.
Immunogen:
Antibacterials
Molecular Weight:
4967
Physical State:
Freeze dried solid
Purity:
>95%
References:
<p>Kahlenberg and Kaplan (2013) Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J. Immunol. <strong>191</strong>(10) 4895 https://doi.org/10.4049/jimmunol.1302005 </p><p>Bandurska et al (2015) Unique features of human cathelicidin LL-37. BioFactors <strong>41</strong> 289 doi:10.1002/biof.1225 </p><p>Chen et al (2018) Roles and Mechanisms of Human Cathelicidin LL-37 in Cancer. Cell Physiol.Biochem. <strong>47</strong> 1060 doi: 10.1159/000490183</p>
Sequence:
Biotin-[PEG(4)]-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH
Shipping Conditions:
Blue Ice
Storage Conditions:
Store frozen, dessicated and in the dark
Size:
1 mg
Supplier:
Isca Biochemicals
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Solubility:
Soluble in water
Formula:
C226H376N64O59S