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Mitochondrial Research

Mitoquinone

A mitochondria-targeted antioxidant displaying cardio- and neuroprotective effects.

 Product Base Number: 10-1363     Size: 5mg     Size: 25mg


Mito-TEMPOMito-TEMPO

A mitochondria-targeted antioxidant targeting reactive oxygen species.

  

Product Base Number: 10-4100       Size: 5mg     Size: 25mg


AT-101AT-101

A small molecule mimic of the BH3 domain of cellular Bcl-2 inhibitors which interferes with the function of Bcl-2-family anti-apoptotic proteins. Induces apoptosis in drug-resistant multiple myeloma cell lines. Apoptosis is activated by the mitochondrial pathway. Cell permeable. 


Product Base Number: 10-1165      Size: 10mg     Size: 50mg


MdiviMdivi

Selective inhibitor of Dnm1 GTPase (IC50=1-10 µM). Inhibits mitochondrial outer membrane permeabilization. Inhibits mitochondrial division and apoptosis. Cell permeable.

 

Product Base Number: 10-1179       Size: 5mg     Size: 25mg


FCCPFCCP

FCCP is a potent and reversible inhibitor of mitochondrial oxidative phosphorylation. It depolarizes mitochondrial membrane potential and induces apoptosis


Product Base Number: 10-1182       Size: 10mg     Size: 50mg


Betulinic AcidBetulinic Acid

Induces mitochondrial permeability pore opening leading to apoptosis in a variety of cell lines.

 

Product Base Number: 10-2278       Size: 10mg     Size: 100mg


Cyclosporine A

Inhibits mitochondrial permeability pore opening inhibiting apoptosis.

Product Base Number: 10-1119       Size: 100mg     Size: 500mg


PK-11195PK-11195

PK-11195 is a selective and potent peripheral benzodiazepine receptor, PBR (or TSPO, translocator protein) antagonist. PK11195 is also able to induce apoptosis in a variety of cell lines

 

Product Base Number: 10-2221       Size: 5mg     Size: 25mg


ObatoclaxObatoclax

Bcl-2 antagonist that overcomes Bcl-2, Bcl-xL, Bcl-w and Mcl-1-mediated resistance to BAX or BAK.

 

Product Base Number: 10-2660       Size: 5mg     Size: 25mg


M-1M-1

Enhances mitochondrial fusion without interfering with endoplasmic reticulum and lysosome morphology.

Product Base Number: 10-598      Size: 5mg     Size: 25mg


N-OleoylphenylalanineN-Oleoylphenylalanine

N-Oleoylphenyalanine is an endogenous uncoupler of UCP1-independent respiration.

 Product Base Number: 10-1602       Size: 5mg     Size: 25mg