VivopureX™ Recombinant Antibodies
Engineered mouse antibodies for in vivo research, available at bulk discounts!
VivopureX™ antibodies are recombinant mouse antibodies ideal for in vivo research in mouse models. The collection consists of popular antibody clones, many originally obtained from rats or hamsters, which Absolute Antibody has engineered into mouse-anti mouse recombinant versions to improve research results.
VivopureX™ recombinant antibodies offer many advantages compared to the original monoclonal antibodies, including increased long-term efficacy, stronger potency and a more consistent response across cohorts. They also feature engineered effector functions, with Fc receptor binding tailored to best suit popular applications such as depletion, agonism or blocking.
The VivopureX™ Antibody Collection
The VivopureX™ collection includes a selection of our most exciting mouse-anti-mouse antibodies, now available at competitively priced bulk prices. All are available in discounted bulk sizes ranging from 1 mg to 100 mg, as well as our standard 200 μg size.
Benefits of Species-Matched Antibodies
Our VivopureX™ antibodies offer many advantages compared to the original antibody format, as illustrated by our data below. In this example, our recombinant mouse PD-1 antibody based on the widely used clone RMP1-14 reduced tumor size in a mouse model more effectively than the original rat version.
- Reduced immunogenicity: no neutralizing antibodies are induced in the host organism, meaning the antibody works for longer and cohorts respond more consistently
- Tailored effector function: the antibody format has been engineered to suit its most popular applications
- Increased potency: less antibody is required to achieve the same response in mouse models
- Batch-to-batch reproducibility: recombinant production ensures the highest possible reproducibility, while guaranteeing high purity and low endotoxin levels
A graph to show the use of VivopureX on tumour volume:
Mean tumor sizes in animals treated with PD-1 mouse IgG2a Fc Silent™ antibody based on clone RMP1-14 (Ab00813-2.3) are significantly smaller than in animals treated with the traditional rat IgG2a antibody (Ab00813-7.1).
Looking for another antibody target for in vivo research? Our catalogue offers many recombinant engineered antibodies against clinically relevant immune checkpoints. Contact us at sales@2bscientific.com.
Antibody Name [Clone] | Engineered Format | Available Bulk Sizes |
|---|---|---|
Mouse IgG1 or IgG2a | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a or Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a | 1, 10, 25, 100mg | |
Mouse IgG2a | 1, 10, 25, 100mg | |
Mouse IgG1 | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG1 | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a | 1, 10, 25, 100mg | |
Mouse IgG2b or Mouse IgG2b Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2b Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2b Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a | 10, 25, 100mg | |
Mouse IgG2a | 10, 25, 100mg | |
Mouse IgG2a | 10, 25, 100mg | |
Mouse IgG2a | 10, 25, 100mg | |
Mouse IgG2a | 10, 25, 100mg | |
Mouse IgG1 Fc Silent™ | 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a or Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2b Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG2a | 1, 10, 25, 100mg | |
Mouse IgG2a | 1, 10, 25, 100mg | |
Mouse IgG2a Fc Silent™ | 1, 10, 25, 100mg | |
Mouse IgG1 | 1, 10, 25, 100mg |