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Antibodies

ELOVL7 Antibody

Product Sizes
100 ug
600-401-AZ8-100UG
About this Product
SKU:
600-401-AZ8
Additional Names:
ELOVL7|ELOVL7 Antibody, Elongation of very long chain fatty acids protein 7, 3-keto acyl-CoA synthase ELOVL7, ELOVL FA elongase 7
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.
Formulation:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Host:
Rabbit
Immunogen:
Anti-ELOVL7 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human ELOVL7.
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Human, Mouse
Shipping Conditions:
Dry Ice
Specificity:
Anti-ELOVL7 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ELOVL7 from other sources has not been determined.
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody
Western Blot of ELOVL7 antibody. Lane 1: Human liver tissue lysate with ELOVL7 antibody at 1 ug/mL. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 33 kDa, 36 kDa for ELOVL7. Other band(s): ELOVL7 splice variants and isoforms.
Immunofluorescence Microscopy of ELOVL7 antibody. Tissue: Human liver tissue. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: ELOVL7 antibody at 20 ug/mL for 1 h at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: ELOVL7 is a membrane protein. Staining: ELOVL7 as red fluorescent signal.
Immunohistochemistry of ELOVL7 antibody. Tissue: human liver tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: ELOVL7 antibody at 5 ug/mL for 1 h at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: ELOVL7 is a membrane protein. Staining: ELOVL7 as precipitated pink signal with blue nuclear counterstain.