SMAD7 Polyclonal Antibody
Product Sizes
SMAD7 Polyclonal Antibody
RD265776A-120UL
About this Product
- SKU:
- RD265776A-120UL
- Additional Names:
- SMAD7,CRCS3,MADH7,MADH8
- Application:
- Immunofluorescence, Western Blot
- Buffer:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human SMAD7 (NP_005895.1).
- Isotype:
- IgG
- Protein Details:
- O15105
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 120 ul
- Supplier:
- Reddot
- Type:
- Antibody
- Synonyms:
- Mothers against decapentaplegic homolog 8;SMAD family member 7
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/32251/SMAD7_Polyclonal_Antibody/
