SPACA3 Polyclonal Antibody
Product Sizes
SPACA3 Polyclonal Antibody
RD252300A-200UL
About this Product
- SKU:
- RD252300A-200UL
- Additional Names:
- 1700025M08Rik,ALLP17,Cancer/testis antigen 54,CT54,LYC3,Lysozyme like sperm specific secretory protein ALLP17,Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17,Lysozyme-like protein 3,LYZL3,processed form,SACA3,SLLP1,SPACA3,Sperm acrosome associated 3,Sperm acrosome membrane-associated protein 3,Sperm lysozyme-like protein 1,Sperm protein reactive with antisperm antibodies,Sperm protein reactive with ASA
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
- Concentration:
- 1.5 mg/ml
- Extra Details:
- SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA or LYZL3, is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic malignancies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms; SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
- Host:
- Rabbit
- Immunogen:
- Full length fusion protein
- Isotype:
- IgG
- Protein Details:
- Q8IXA5
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 200 ul
- Supplier:
- Reddot
- Type:
- Antibody
- Synonyms:
- Cancer/testis antigen 54;Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17;Lysozyme-like protein 3;Sperm lysozyme-like protein 1;Sperm protein reactive with antisperm antibodies
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/31274/SPACA3_Polyclonal_Antibody/