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Antibodies

SPACA3 Polyclonal Antibody

Product Sizes
SPACA3 Polyclonal Antibody
RD252300A-200UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
RD252300A-200UL
Additional Names:
1700025M08Rik,ALLP17,Cancer/testis antigen 54,CT54,LYC3,Lysozyme like sperm specific secretory protein ALLP17,Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17,Lysozyme-like protein 3,LYZL3,processed form,SACA3,SLLP1,SPACA3,Sperm acrosome associated 3,Sperm acrosome membrane-associated protein 3,Sperm lysozyme-like protein 1,Sperm protein reactive with antisperm antibodies,Sperm protein reactive with ASA
Application:
ELISA, Immunohistochemistry
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration:
1.5 mg/ml
Extra Details:
SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA or LYZL3, is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic malignancies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms; SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
Host:
Rabbit
Immunogen:
Full length fusion protein
Isotype:
IgG
Protein Details:
Q8IXA5
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Size:
200 ul
Supplier:
Reddot
Type:
Antibody
Synonyms:
Cancer/testis antigen 54;Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17;Lysozyme-like protein 3;Sperm lysozyme-like protein 1;Sperm protein reactive with antisperm antibodies