Purified Anti-Human CD279/PD-1 Monoclonal Antibody
Product Sizes
Purified Anti-Human CD279/PD-1 Monoclonal Antibody
RD22250F-25UG
About this Product
- SKU:
- RD22250F-25UG
- Additional Names:
- PDCD1,PD1,Protein PD-1,hPD-1
- Application:
- Flow Cytometry, Immunohistochemistry
- Buffer:
- PBS with 0.05% Proclin300
- translate.label.attr.clone:
- J110
- Clonality:
- Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
- Gene Details:
- ITGAL
- Host:
- Mouse
- Isotype:
- IgG1, kappa
- Protein Details:
- P20701
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Size:
- 25 ug
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Synonyms:
- antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide;CD11 antigen-like family member A;CD11A;integrin alpha-L;integrin gene promoter;integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide);leukocyte adhesion glycoprotein LFA-1 alpha chain;leukocyte function-associated molecule 1 alpha chain;LFA-1;LFA-1 alpha;LFA1A;LFA-1A;lymphocyte function-associated antigen 1, alpha polypeptide