Anti-Hu CD99 PE
Product Sizes
100 tests
AFC-ZGKCP0-100TESTS
About this Product
- SKU:
- AFC-ZGKCP0
- Additional Names:
- MIC2, HBA71, blood group Xg
- Application:
- Flow Cytometry
- Buffer:
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- translate.label.attr.clone:
- 3B2/TA8
- Clonality:
- monoclonal
- Conjugate:
- PE
- Extra Details:
- CD99 is a ubiquitous transmembrane type I sialoglycoprotein of a unique and poorly characterized protein family. CD99 is heavily O-glycosylated and was described as a T cell costimulator and strong activator of integrin-mediated actin cytoskeleton assembly, promoting cell adhesion and homotypic aggregation, immediate arrest on an inflamed vascular endothelium, and cell migration through it. Ligation of CD99 under some conditions can lead to apoptosis. Originally CD99 was described as a human thymus leukemia antigen, an Ewing´s sarcoma-specific membrane marker, and an adhesion molecule involved in spontaneous rosette formation of T cells with erythrocytes.
- Format:
- PE
- Immunogen:
- Human thymocytes
- Isotype:
- IgG2a k
- Purification:
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Research Area:
- Immunology
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 3B2/TA8 recognizes an extracellular epitope of CD99, an approximately 32 kDa sialoglycoprotein expressed on the surface of many cell types, with particularly strong expression on Ewing´s sarcoma and peripheral primitive neuroectodermal tumors. Within the hematopoietic system, CD99 is expressed on virtually all cell types except granulocytes.
- Storage Conditions:
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Nordic BioSite
- Manufacturer's Data Sheet:Anti-Hu CD99 PE