Anti-Hu CD271 PE
Product Sizes
100 tests
AFC-1N3RQ3-100TESTS
About this Product
- SKU:
- AFC-1N3RQ3
- Additional Names:
- TNFRSF16, NGFR, p75NTR, p75NGFR
- Application:
- Flow Cytometry
- Buffer:
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- translate.label.attr.clone:
- NGFR5
- Clonality:
- monoclonal
- Conjugate:
- PE
- Extra Details:
- CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
- Format:
- PE
- Immunogen:
- Purified CD271 protein isolated from human melanoma cell line A875
- Isotype:
- IgG1
- Purification:
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Research Area:
- Neuroscience
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.
- Storage Conditions:
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Nordic BioSite
- Manufacturer's Data Sheet:Anti-Hu CD271 PE
