AF/LE Purified Anti-Mouse CD8a Antibody[53-6.7]
Product Sizes
25 ug
E-AB-F11040-25UG
100 ug
E-AB-F11040-100UG
1 mg
E-AB-F11040-1MG
5 mg
E-AB-F11040-5MG
25 mg
E-AB-F11040-25MG
50 mg
E-AB-F11040-50MG
100 mg
E-AB-F11040-100MG
About this Product
- SKU:
- E-AB-F11040
- Additional Names:
- T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL
- Application:
- Flow Cytometry
- Buffer:
- Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- 53-6.7
- Clonality:
- Monoclonal
- Concentration:
- >= 1 mg/ml
- Extra Details:
- CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked A Alpha and B Beta chains that form the A Alpha(CD8a)/B Beta(CD8b) heterodimer and A Alpha/A Alpha homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 A Alpha/B Beta heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR A Alpha/B Beta T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 A Alpha/A Alpha homodimer is expressed on a subset of G Gamma/D Delta TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
- Host:
- Rat
- Immunogen:
- CD8a
- Isotype:
- IgG2a, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:WXn1KS
