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Antibodies

anti-CD45 antibody [MEM-28] (APC)

Product Sizes
100 tests
ARG53854-100TESTS
Academic Pricing
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About this Product
SKU:
ARG53854
Additional Names:
LY5; GP180; Receptor-type tyrosine-protein phosphatase C; CD45; L-CA; CD antigen CD45; Leukocyte common antigen; CD45R; LCA; T200; EC 3.1.3.48; B220
Application:
Flow Cytometry
Buffer:
PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
CE/IVD:
RUO
translate.label.attr.clone:
MEM-28
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Host:
Mouse
Immunogen:
Human thymocytes and T lymphocytes.
Isotype:
IgG1
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The clone MEM-28 reacts with all alternative forms of human CD45 antigen (Leukocyte Common Antigen), a 180-220 kDa single chain type I transmembrane protein expressed at high level on all cells of hematopoietic origin, except erythrocytes and platelets. HLDA III; WS Code NL 833a
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody
Flow Cytometry: Human peripheral whole blood stained with ARG53854 anti-CD45 antibody [MEM-28] (APC) (10 ul reagent / 100 ul of peripheral whole blood).
Flow Cytometry: Separation of Human CD45 positive Lymphocytes (red) from Human CD45 negative blood debris (black-dashed). Human peripheral whole blood stained with ARG53854 anti-CD45 antibody [MEM-28] (APC) (10 ul reagent / 100 ul of peripheral whole blood).
Flow Cytometry: Human peripheral blood cells stained with ARG53854 anti-CD45 antibody [MEM-28] (APC).