anti-Cardiac Troponin I phospho (Ser43) antibody
About this Product
- SKU:
- ARG52455
- Additional Names:
- RCM1; cTnI; Cardiac troponin I; TNNC1; CMD1FF; CMD2A; Troponin I, cardiac muscle; CMH7
- Application:
- Western Blot
- Buffer:
- 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Troponin I (TnI) is 1 of 3 subunits, along with troponin C (TnC) and Troponin T (TnT) of troponin complex found in cardiac (cTnI) and fast skeletal (fsTnI) muscle (Noland et al, 1995). Protein kinase C-mediated phosphorylation of cardiac myofilament proteins has been shown to depress the actomyosin interaction and may be important during heart failure. (Montgomery et al, 2002) Studies indicate that phosphorylation of Ser43 and Ser45 of cardiac troponin I plays a substantial role in the PKCmediated depression. (Montgomery et al, 2002).
- Host:
- Rabbit
- Immunogen:
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser43 conjugated to KLH
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Amphibian, Bovine, Canine, Fish, Human, Mouse, Non-human Primate, Rat, Sheep
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG52455.html
