anti-EphrinB phospho (Tyr331) antibody
About this Product
- SKU:
- ARG52275
- Additional Names:
- EPH-like kinase 5; Developmentally-regulated Eph-related tyrosine kinase; Hek5; Renal carcinoma antigen NY-REN-47; EPH tyrosine kinase 3; Tyrosine-protein kinase receptor EPH-3; DRT; ELK-related tyrosine kinase; Tyrosine-protein kinase TYRO5; Ephrin type-B receptor 2; hEK5; PCBC; EPHT3; Tyro5; EK5; EC 2.7.10.1; CAPB; ERK
- Application:
- Western Blot
- Buffer:
- 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- EphrinB proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development (Flanagan and Vanderhaeghen, 1998; Dufour et al., 2003; Oike et al., 2002). EphrinB molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cell-to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing EphrinB on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of EphrinB is thought to be a critical component of this reverse signaling event (Palmer et al., 2002). Recent work demonstrated that Tyr331 of EphrinB was phosphorylated in HEK293 cells after stimulation by the soluble EphB2 receptor tyrosine kinase (Kalo et al., 2001)
- Host:
- Rabbit
- Immunogen:
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr331 conjugated to KLH
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Amphibian, Avian, Bovine, Fish, Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG52275.html
