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Antibodies

anti-CD137 antibody [4B4-1] (APC)

Product Sizes
50 tests
ARG42319-50TESTS
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG42319
Additional Names:
ILA; CD137; T-cell antigen 4-1BB homolog; CDw137; T-cell antigen ILA; 4-1BB; CD antigen CD137; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor
Application:
Flow Cytometry
Buffer:
PBS and 15 mM Sodium azide.
CE/IVD:
RUO
translate.label.attr.clone:
4B4-1
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
Recombinant Human CD137 ectodomain.
Isotype:
IgG1, kappa
Purification:
Purified
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody 4B4-1 recognizes an extracellular conformational epitope on CD137, an approximately 40 kDa type I transmembrane protein of the TNFR family expressed mainly on activated T cells.
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody
Flow Cytometry: Human PHA stimulated peripheral blood mononuclear cell suspension stained with ARG42319 anti-CD137 antibody [4B4-1] (APC) at 10 ul / 10^6 cells in 100 ul of cell suspension.
Flow Cytometry: Human peripheral blood mononulcear cells stained with ARG42319 anti-CD137 antibody [4B4-1] (APC) at 10 ul / 10^6 cells in 100 ul of cell suspension and ARG53801 anti-CD25 antibody [MEM-181] (PE) at 20 ul / 10^6 cells in 100 ul of cell suspension.
Flow Cytometry: Human PHA stimulated peripheral blood mononuclear cell suspension. Separation of cells stained with ARG42319 anti-CD137 antibody [4B4-1] (APC) at 10 ul / 10^6 cells in 100 ul of cell suspension (red-filled) from cells stained with ARG65336 Mouse IgG1 Kappa Isotype Control antibody [MOPC-21] (APC) at 1 ug/ml dilution (black-dashed).