anti-Ly6G + Ly6C antibody [RB6-8C5] (APC-Cyanine 7)
About this Product
- SKU:
- ARG22112
- Additional Names:
- Gr1; Gr-1; Ly-6G
- Application:
- Depletion, Flow Cytometry, IHC-Frozen
- Buffer:
- PBS, 0.1% Sodium azide and Sucrose.
- CE/IVD:
- RUO
- translate.label.attr.clone:
- RB6-8C5
- Clonality:
- Monoclonal
- Conjugate:
- APC-Cyanine 7
- Concentration:
- 0.1 mg/ml
- Extra Details:
- Ly6G is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. Ly6G is a good marker for detection of peripheral neutrophils. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Physiological role of Ly6G remains still unclear. Its treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses.
- Host:
- Rat
- Immunogen:
- Ly6G + Ly6C
- Isotype:
- IgG2b, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody recognizes the mouse Gr-1 antigen, a ~21 - 25 kDa GPI anchored cell surface protein bearing a single uPAR/Ly6 domain that belongs to the Ly-6 family of proteins (Lee et al. 2013). Clone RB6-8C5 reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been reported (Fleming et al. 1993). However, other observations dispute the cross-reactivity of cl
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG22112.html
