SARS-CoV-2 Spike Trimer Protein (C136F, Y144del, R190S, D215G, LA242-243del, Y449H, E484K, N501Y, D614G, H655Y, N679K, T716I, T859N), His Tag (MALS verified)
Product Sizes
50 ug
SPN-C52HB-50UG
500 ug
SPN-C52HB-500UG
About this Product
- SKU:
- SPN-C52HB
- Additional Names:
- S glycoprotein|S protein|Spike|Spike glycoprotein
- Buffer:
- 0.1 M Sodium citrate, pH5.5
- Extra Details:
- SARS-CoV-2 Spike Trimer, His Tag (SPN-C52Hb) is the ectodomain of SARS-CoV-2 spike protein which contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The mutations C136F, Y144del, R190S, D215G, LA242-243del, Y449H, E484K, N501Y, D614G, H655Y, N679K, T716I, T859N were identified in the SARS-CoV-2 variant C.1.2. The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
- Immunogen:
- Spike protein
- Molecular Weight:
- 137.6 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
