Anti-Fibronectin [BC-1]
Product Sizes
500 ug
AB03457-10-29-BT-500UG
About this Product
- SKU:
- AB03457-10-29-BT
- Additional Names:
- FN; EDB(+) FN; ED-B domain of fibronectin; Extra domain-B containing fibronectin; oncofetal fibronectin; cold-insoluble globulin; CIG; BC1; HuBC-1
- Application:
- Immunohistochemistry, Radioimmunoassay, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- BC-1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original mouse antibody was generated by immunizing mice with fibronectin derived from a culture medium of SV40-transformed Wi-38 embryonic human lung cells and defined Wi-38Val3. The humanized version was generated later by grafting CDRs of original mouse antibody onto human framework regions.
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is selective for a cryptic epitope in domain 7 of the B-form splice variant ED-B sequence of fibronectin (EDB-FN). This antibody does not react with plasma fibronectin or thermolysin-digested fibronectin from Wi-38 or Wi-38Val3 cells. Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. They are involved in cell adhesion, cell mot
- Storage Conditions:
- 2-8[o]C
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03457-10.29-BT
