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Vector Laboratories

Vector Laboratories develops, manufactures and markets labelling and detection reagents for immunohistochemistry, immunofluorescence, DNA/RNA and glycobiology. The company serves customers in disease and therapeutics research with tools that help them precisely visualise and study tissues and cells. A pioneer in a number of innovative technologies, Vector Laboratories has been providing a continuous stream of reliable biomedical research tools for more than 40 years. With headquarters in Burlingame, California and a subsidiary in Peterborough, UK, the company maintains a global outreach. A privately held company, Vector Laboratories was acquired by Maravai LifeSciences in 2016.

Vector Laboratories

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Vector Laboratories
Introducing VECTASHIELD® Vibrance™ Antifade Mounting Media

VECTASHIELD Vibrance products are completely new formulations of curing antifade mounting media for immunofluorescence applications. These newest additions to our VECTASHIELD portfolio were developed with customer feedback to improve on parameters such as ease of use and retention of specific staining intensity over time. VECTASHIELD Vibrance Antifade Mounting Media are new tools to help investigators see more and do more with each experiment. 

Why VECTASHIELD Vibrance Mounting Media?

- Superior antifade/anti-photobleaching properties across the spectrum

- Compatibility with commonly used fluorophores

- View sections one hour after mounting

- No tone or autofluorescent background, even after curing

- Room temperature storage of slides with extended archiving time

- Minimal bubble formation, even after several weeks storage

- Curing formulations with choice of counterstain (DAPI) or no counterstain

- 12 month product expiration date

Plus the same features you have come to expect of VECTASHIELD® brand:

- Ideal refractive index

- Easy to use

- Ready to use, requires no warming

- No sealing of coverslips required (curing formulations)

 

Easy Application and Use of VECTASHIELD Vibrance
Vector Laboratories
Excellent Antifade Properties Across the Spectrum, with Commonly Used Fluorophores

VECTASHIELD Vibrance Mounting Media provide excellent protection against fading across the visible spectrum, even under far-red wavelengths. They are compatible with most commercially available fluorophores.
 

Fluorophore

 

Excitation/Emission (nm)

 

Vectashield® Vibrance™ (H-1700)

 

Vectashield® Vibrance™ with DAPI (H-1800)

 

 

 

 

 

 

 

Fluorescein

 

495/515

 

++++

 

++++

 

 

 

 

 

 

 

Alexa Fluor® 488

 

490/525

 

+++

 

+++

 

 

 

 

 

 

 

Dylight® 488

 

493/518

 

+++

 

+++

 

 

 

 

 

 

 

Cy® 3

 

550/570

 

++++

 

++++

 

 

 

 

 

 

 

Alexa Fluor® 594

 

590/617

 

++++

 

++++

 

 

 

 

 

 

 

Dylight® 594

 

593/618

 

++++

 

++++

 

 

 

 

 

 

 

Cy® 5

 

649/670

 

++++

 

++++

 

 

 

 

 

 

 

Alexa Fluor® 647

 

650/665

 

++++

 

++++

 

 

 

 

 

 

 

Dylight® 649

 

652/672

 

++++

 

++++


Viewable in as Little as One Hour After Mounting – No Need to Wait 24 Hours


Competitor immunofluorescence workflows recommend slides be viewed 24 hours after mounting. VECTASHIELD Vibrance Mounting Media, however, allow same-day viewing to accelerate discovery without sacrificing signal intensity or retention.

Vector Laboratories

Improved retention of fluorescence with VECTASHIELD Vibrance Mounting Medium. Serial sections of human colon tissue (FFPE) stained for cytokeratin (mouse primary antibody AE1/AE3) and detected with fluorescein-conjugated horse anti-mouse IgG secondary antibody (FI-2000). One hour after mounting with either VECTASHIELD Vibrance (top row) or a competitor mounting medium (bottom row), the sections were imaged at the intervals indicated. Note the improved retention of fluorescent signal for sections mounted with VECTASHIELD Vibrance Mounting Medium.

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