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Antibodies

Histone H2A pan Antibody

Product Sizes
50 ug
600-401-X48-50UG
About this Product
SKU:
600-401-X48
Additional Names:
HIST1H2AB|Histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m, H2AFM, HIST1H2AE, H2AFA
Application:
ChIP, ELISA, Immunofluorescence, Western Blot
Buffer:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
0.64 mg/ml
Extra Details:
Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histones play a internal role in the regulation of transcription, DNA repair, DNA replication and chromosomal stability. These different functions are established via a complex set of post-translational modifications which either directly or indirectly alter chromatin structure and DNA accessibility to facilitate transcriptional activation or repression or other nuclear processes. Anti-Histone H2A pan Antibody is ideal for research in Chromatin Remodeling, Gene Expression and Epigenetics.
Formulation:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Host:
Rabbit
Immunogen:
Anti-Histone H2A pan Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing a sequence from the C-terminus of histone H2A.
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Human
Shipping Conditions:
Dry Ice
Specificity:
Anti-Histone H2A pan Antibody was purified by affinity purification. Cross reactivity with other species was not tested.
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody