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Proteins and Peptides

14-3-3 theta protein-GST fusion

Product Sizes
20 ug
009-001-R29S-20UG
About this Product
SKU:
009-001-R29S
Additional Names:
14-3-3 theta, YWHAQ, 1C5, HS1, 14-3-3, 14-3-3 protein tau|YWHAQ
Application:
Western Blot
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
0.2 ug/ul
Extra Details:
14-3-3Q Theta (also known as tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. Through interaction with ASK1, c-jun NH-terminal kinase, and p38 mitogen-activated protein kinase (MAPK), 14-3-3Q Theta plays an important role in controlling apoptosis (1). Induced expression of 14-3-3Q Theta protein has been reported in patients with amyotrophic lateral sclerosis. Additionally, 14-3-3Q Theta has been observed to mediate nucleocytoplasmic shuttling of the N protein (coronavirus nucleocapsid protein) which causes severe acute respiratory syndrome (2). 14-3-3Q Theta Protein is ideal for investigators involved in Cell Stress& Chaperone Proteins, AKT/PKB Pathway, Cancer, Cell Cycle, Cellular Stress, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, and WNT Signaling research.
Immunogen:
YWHAQ
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Specificity:
Recombinant full-length human 14-3-3Q Theta was expressed in E. coli cells using an N-terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >95% by densitometry.
Storage Conditions:
-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins