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Antibodies

Purified Anti-Human CD86 Monoclonal Antibody

Product Sizes
Purified Anti-Human CD86 Monoclonal Antibody
RD20251F-25UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
RD20251F-25UG
Additional Names:
T-lymphocyte activation antigen CD86,Cd86,Activation B7-2 antigen,Early T-cell costimulatory molecule 1,ETC-1
Application:
Block/Inhibit/Neutralise, Flow Cytometry, Immunoprecipitation, Western Blot
Buffer:
PBS with 0.05% Proclin300
translate.label.attr.clone:
BU63
Clonality:
Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Gene Details:
CD86
Host:
Mouse
Isotype:
IgG1, kappa
Protein Details:
P42081
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Size:
25 ug
Supplier:
Reddot
Type:
Antibody: Monoclonal Antibody
Synonyms:
Activation B7-2 antigen;B7.2;B70;B7-2;B-lymphocyte activation antigen B7-2;BU63;CD28LG2;CD86 antigen (CD28 antigen ligand 2, B7-2 antigen);CTLA-4 counter-receptor B7.2;FUN-1;LAB72;T-lymphocyte activation antigen CD86