FITC Anti-Human CD45 Antibody[HI30]
Product Sizes
20 tests
E-AB-F1137C-20T
100 tests
E-AB-F1137C-100T
2 x 100 tests
E-AB-F1137C-2X100T
About this Product
- SKU:
- E-AB-F1137C
- Additional Names:
- CD45;L-CA;Ly-5;Ptprc;Receptor-type tyrosine-protein phosphatase C;T200
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- HI30
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Concentration:
- 5 ul/test
- Extra Details:
- CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
- Host:
- Mouse
- Immunogen:
- CD45
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:CGqP4G
