Anti CD63 Antigen (LAMP-3/Tspan-30) monoclonal antibody (Clone 8A12)
Product Sizes
50 ul
CAC-SHI-EXO-M02-50-50UL
About this Product
- SKU:
- CAC-SHI-EXO-M02-50
- Application:
- Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
- translate.label.attr.clone:
- Clone 8a12
- Clonality:
- Monoclonal
- Extra Details:
- Click here for more information and to see all exosome related products from Cosmo Bio USA. CD63 (also known as LAMP-3, Melanoma-associated antigen ME491, TSPAN30, MLA1 and OMA81H) is a cell surface glycoprotein which belongs to the tetraspanin superfamily. CD63 is known to complex with integrins. CD63 is expressed on activated platelets, monocytes and macrophages and is weakly expressed on granulocytes, T cells and B cells. Importantly, it is found on the surface of exosomes. Exosomes are cell-derived vesicles bounded by a lipid bilayer membrane and exhibiting a diameter of 50 to 150 nm. They are secreted from cultured cells and are observed in body fluids such as saliva, blood, urine, amniotic fluid, malignant ascites. Recent studies indicate that exosomes contain various proteins and RNAs, suggesting a role in information transfer between cells. This monoclonal antibody can be used to immunoprecipitate exosomes from serum and culture supernatants. References: 1) Yoshioka Y et al., Nat Commun. 2014 Apr 7;5:3591. doi: 10.1038/ncomms4591. 2) N Nishida-Aoki et al., Mol Ther. 2017 Jan 4;25(1):181-191. doi: 10.1016/j.ymthe.2016.10.009. 3) Saito S et al., Sci Rep. 2018 Mar 5;8(1):3997. doi: 10.1038/s41598-018-22450-2., CAC
- Host:
- Mouse
- Immunogen:
- CD63 Antigen (LAMP-3/Tspan-30)
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -70[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Monoclonal Antibody