Anti-Alpha-ketoglutarate-dependent dioxygenase FTO [5-2H10]
Product Sizes
1 mg
AB02550-10-3-BT-1MG
About this Product
- SKU:
- AB02550-10-3-BT
- Additional Names:
- FTO; Fat mass and obesity-associated protein; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; m6A(m)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO
- Application:
- Immunocytochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 5-2H10
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- This antigen was raised by immunizing a BALB/c mouse with the alpha-ketoglutarate-dependent dioxygenase FTO antigen.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for the alpha-ketoglutarate-dependent dioxygenase FTO. This protein is a RNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass, adipogenesis and energy homeostasis. Specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA
- Storage Conditions:
- 2-8[o]C
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02550-10.3-BT