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Antibodies

Anti-CTLA-4 [9H10]

Product Sizes
200 ug
AB00894-2-0-200UG
About this Product
SKU:
AB00894-2-0
Additional Names:
CD152; CTLA4; cytotoxic T-lymphocyte-associated antigen 4; Cytotoxic T-lymphocyte protein 4
Application:
Block/Inhibit/Neutralise, ELISA, Flow Cytometry, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
9H10
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric mouse antibody was made using the variable domain sequences of the original Hamster IgG2 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
This antibody was raised by immunising Syrian hamsters with Staphylococcus A bacteria coated in CTLA-4, isolating B cells from the immunised hamsters and fusing these with the P3X3.Ag8.653 myeloma line to produce stable hybridomas.
Isotype:
IgG2a
Purification:
Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for murine CTLA-4, an inhibitory receptor that acts as the primary negative regulator of T-cell responses. CTLA-4 is expressed predominantly by activated T cells, with significantly higher levels of expression on CD8+ T cells than CD4+ T cells.
Storage Conditions:
2-8[o]C Aliquot.
Type:
Antibody: Recombinant Antibodies