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Proteins and Peptides

SARS-CoV-2 Spike Trimer Protein (K417N, D614G), His Tag (MALS verified)

Product Sizes
50 ug
SPN-C52HM-50UG
500 ug
SPN-C52HM-500UG
About this Product
SKU:
SPN-C52HM
Additional Names:
S glycoprotein|S protein|Spike|Spike glycoprotein
Buffer:
0.1 M Sodium citrate, pH5.5
Extra Details:
SARS-CoV-2 S protein (K417N,D614G), His Tag (SPN-C52Hm) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The mutations (K417N, D614G) were identified in the SARS-CoV-2 variant (known as B.1.351 or 20C/501Y.V2) which emerged in South Africa. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
Immunogen:
Spike protein
Molecular Weight:
138.0 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SARS-CoV-2 Spike Trimer (K417N, D614G), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human ACE2, Fc Tag (Cat. No. AC2-H5257) at 1 ug/mL (100 uL/well) can bind SARS-CoV-2 Spike Trimer , His Tag (Cat. No. SPN-C52Hm) with a linear range of 1.6-50 ng/mL (QC tested).
Immobilized SARS-CoV-2 Spike Trimer , His Tag (Cat. No. SPN-C52Hm) at 1 ug/mL (100 uL/well) can bind Human ACE2, Fc Tag (Cat. No. AC2-H5257) with a linear range of 3.1-50 ng/mL (Routinely tested).