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Antibodies

JAKMIP1 Antibody

Product Sizes
100 ug
600-401-CB1-100UG
About this Product
SKU:
600-401-CB1
Additional Names:
JAKMIP1|JAKMIP1 Antibody, JAMIP1, MARLIN1, Gababrbp, GABABRBP, JAMIP1, Janus kinase and microtubule-interacting protein 1, GABA-B receptor-binding protein, Marlin-1
Application:
ELISA, Western Blot
Buffer:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
Formulation:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Host:
Rabbit
Immunogen:
Anti- JAKMIP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the internal region of human JAKMIP1.
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Dry Ice
Specificity:
Anti-JAKMIP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Multiple isoforms of JAKMIP1 are known to exist. JAKMIP1 antibody is predicted to not cross-react with JAKMIP2.
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody