MIP-3 alpha Antibody
Product Sizes
25 ul
210-501-B51S-25UL
About this Product
- SKU:
- 210-501-B51S
- Additional Names:
- Ccl20|rat anti-MIP-3A Alpha antibody, CCL20, C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1
- Application:
- Western Blot
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 4N5F7
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- MIP-3A Alpha (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3A Alpha inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3A Alpha also possesses antibacterial activity against E.coli and S.aureus. MIP-3A Alpha is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Rat
- Immunogen:
- Anti-MIP-3A Alpha (RAT) Monoclonal Antibody was produced in rat by repeated immunizations with mature full length recombinant mouse MIP-3A Alpha produced in E.coli followed by hybridoma development.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Mouse
- Shipping Conditions:
- Dry Ice
- Specificity:
- This product was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for mouse MIP-3A Alpha protein. A BLAST analysis was used to suggest cross-reactivity with MIP-3A Alpha from mouse sources based on 100% homology with the immunizing sequence. Cross-reactivity with MIP-3A Alpha fr
- Storage Conditions:
- -20[o]C diluted. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=210-501-B51S
