Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

BG37 Antibody

Product Sizes
100 ul
100-401-H59-100UL
About this Product
SKU:
100-401-H59
Additional Names:
GPBAR1|TGR5, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, hGPCR19, Membrane-type receptor for bile acids, M-BAR, hBG37, BG37
Application:
Western Blot
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
Anti-BG37 TGR5 Antibody detects human BG37tgr5. BG37 is a 330 amino acid novel enzyme with seven transmembrane domains. It belongs to the G protein-coupled receptor (GPCR) superfamily and functions as a cell surface receptor for bile acids. Cells expressing BG37 when treated with bile acids induce the production of intracellular cAMP, activate the MAP kinase signaling pathway, leads to the internalization of the receptor and regulates proglucagon gene expression in enteroendocrine cells. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids that can be targeted to improve metabolic control. It is known to be ubiquitously expressed in most of the tissues. Anti-BG37 TGR5 Antibody is ideal for investigators involved in kinase, phosphatase, and NFkappaB research.
Format:
Antiserum
Host:
Rabbit
Immunogen:
BG37 Antibody was produced from whole rabbit serum which was prepared by repeated immunizations with the amino acid portion of human BG37 near the C-terminus of the chain .
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Dry Ice
Specificity:
Anti-BG37 Antibody is sera. A BLAST analysis was used to suggest cross-reactivity with BG37 from human and mouse based on 100% homology with the immunizing sequence. Predicted reactivity with cow. Cross-reactivity with BG37 from other sources has not been determined.
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody