CTLA-4 monoclonal antibody (9D9), InVivoPure
Product Sizes
1 mg
AK3609P-1MG
5 mg
AK3609P-5MG
25 mg
AK3609P-25MG
50 mg
AK3609P-50MG
100 mg
AK3609P-100MG
About this Product
- SKU:
- AK3609P
- Additional Names:
- Anti-Mouse CTLA-4, CD152, CTLA4, cytotoxic T-lymphocyte-associated antigen 4, Cytotoxic T-lymphocyte protein 4
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS
- translate.label.attr.clone:
- 9D9
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The CTLA-4 antibody (clone 9D9) is a monoclonal antibody that specifically targets the mouse CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152 [1]. CTLA-4 is a 33 kDa cell surface receptor, belonging to the CD28 family of the immunoglobulin superfamily. CTLA-4 plays a crucial role in immune regulation. 9D9 blocks the binding of murine CTLA-4-Ig to B7-1-positive cells [2]. It has an inhibitory effect and acts as an "off switch" for T cells. It binds to the ligands CD80 and CD86 on antigen-presenting cells (APCs) and thereby inhibits the activation of T cells . The CTLA-4 antibody clone 9D9 has been used to block CTLA-4 and has been shown to enhance T-cell immunity against tumors .
- Formulation:
- Clear Liquid, PBS, pH 7.4, 0.2 um sterile filtered
- Host:
- Mouse
- Immunogen:
- Not Known
- Isotype:
- IgG2b
- Physical State:
- Liquid
- Purity:
- >=90%
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- InVivo Biotech Services GmbH
- Type:
- Antibody: In Vivo Antibodies
- Shipping Costs:
- Free Shipping to the UK
- Main Competitor:
- This product is an equivalent to the main competitor item
