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Antibodies

Anti-Synapsin (Ser549) Antibody

Product Sizes
25 ul
p1560-549-25UL
100 ul
p1560-549-100UL
About this Product
SKU:
p1560-549
Additional Names:
Brain protein 4.1 antibody, SYN 1 antibody, SYN 1a antibody, SYN 1b antibody, SYN I antibody, SYN1 antibody, SYN1_HUMAN antibody, SYN1a antibody, SYN1b antibody, Synapsin 1 antibody, Synapsin I antibody, Synapsin-1 antibody, Synapsin1 antibody, SynapsinI antibody, SYNI antibody
Application:
Immunocytochemistry, Western Blot
Buffer:
10 mm hepes
CE/IVD:
RUO
Clonality:
Polyclonal
Conjugate:
Ser549 - Phosphorylated
Extra Details:
Our Anti-Synapsin (Ser549) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects mouse and rat Synapsin (Ser549) and is antigen affinity purified from pooled serum. It is great for use in WB, ICC.
Format:
Antigen Affinity Purified from Pooled Serum
Gene Details:
SYN1
Host:
Rabbit
Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser549 of rat synapsin, conjugated to keyhole limpet hemocyanin (KLH).
Isotype:
IgG
Molecular Weight:
78
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Bovine, Canine, Human, Mouse, Non-human Primate, Rat
Shipping Conditions:
Blue Ice
Specificity:
Specific for endogenous levels of the ~78 kDa synapsin I doublet phosphorylated at Ser549. Immunolabeling is completely eliminated by treatment with L Lambda-phosphatase.
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Type:
Antibody: Polyclonal Antibody
Immunostaining of cultured mouse caudate neurons showing synapsin I when phosphorylated at Ser549(cat. p1560-549, green, 1:500). Cells and photo courtesy of QBMCellScience.
In vivo inhibition of Cdk5 assessed via quantitative immunoblot for P-Ser549 (cat. p1560-549)/total Synapsin I in rat hippocampus after treatment with 50 mg/kg 25-106. Image from publication CC-BY-4.0. PMID: 36854738
Western blot of rat cortical lysate showing specific immunolabeling of the ~78 kDa synapsin I phosphorylated at Ser549 in the first lane (-). Phosphospecificity is shown in the second lane (+) where the immunolabeling is completely eliminated by blot treatment with lambda phosphatase (L Lambda-Ptase, 1200 units for 30 minutes).