14-3-3 Protein Antibody (Phospho-Ser58)
Product Sizes
14-3-3 Protein Antibody (Phospho-Ser58)
£ POA
OAPC00178
About this Product
- SKU:
- OAPC00178
- Application:
- Immunofluorescence, Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Format:
- Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.
- Gene Details:
- YWHAB
- Host:
- Rabbit
- Molecular Weight:
- ~29kDa
- Protein Details:
- 14-3-3 protein beta/alpha
- Purification:
- Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
- References:
- Berg D, Holzmann C, Riess O (2003) 14-3-3 Proteins in the nervous system. Nat Rev Neurosci 4:752-762.<br/>Bridges D, Moorhead GB (2005) 14-3-3 Proteins: a number of functions for a numbered protein. Sci STKE 2005:re10.<br/>Dougherty MK, Morrison DK (2004) Unlocking the code of 14-3-3. J Cell Sci 117:1875-1884.<br/>Silhan J, Obsilova V, Vecer J, Herman P, Sulc M, Teisinger J, Obsil T (2004) 14-3-3 Protein C-terminal stretch occupies ligand binding groove and is displaced by phosphopeptide binding. J Biol Chem 279:49113-49119.<br/>Woodcock JM, Murphy J, Stomski FC, Berndt MC, Lopez AF (2003) The dimeric versus monomeric status of 14-3-3 zeta is controlled by phosphorylation of Ser58 at the dimer interface. J Biol Chem 278:36323-36327.<br/>Xiangjun Yang, Cheng Luo, Jian Cai, William M. Pierce, and Gülgün Tezel (2008) Phosphorylation-Dependent Interaction with 14-3-3 in the Regulation of Bad Trafficking in Retinal Ganglion Cells. Invest. Ophthalmol. Vis. Sci., 49: 2483 - 2494.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C; stable for at least one year.
- Supplier:
- Aviva Systems Biology
- Manufacturer's Data Sheet:html_datasheet.php
