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Focus Biomolecules

Focus Biomolecules was founded by former members of globally recognised BIOMOL. From their industry experience they set out to refine the practices of small molecule based life sciences companies and eliminate the challenges too often found by customers.

With more than 24 years in the industry, they offer advanced, high quality reagents and a fresh, customer oriented experience.

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Focus Biomolecules

Essential Biochemicals for Bioprocessing

 

Focus Biomolecules offer a broad portfolio of cutting-edge biochemicals with specific utility in bio-processing. Their bioprocessing agents will allow you control cell selection, growth, and function which will maximize protein expression, yield, glycosylation, integrity and minimize degredation, both upstream and downstream. Key product groups include:
 

Antibiotics & Antifungals
Cell cycle modulators
Ionophores
Cofactors & Coenzymes
Glycosylation inhibitors
Selection & Amplification reagents
Apoptosis & Autophagy Modulators
Protease inhibitors
Differentiation agents
Cell growth modulators
Protein expression modulators
Stem Cell Effectors

Bioprocessing

These products can be used to establish conditions during early stage assessment and upstream process development, to ensure optimization at every step. These include chemically defined medium design, feed/supplement selection, expression host selection, lead candidate production, process optimization, scaleup and validation.

Below is just a selection of our bioprocessing chemicals. You won't see these listed with other bioprocessing suppliers, because these are on the cutting-edge for controlling protein titer, post-translational modification, and other critical parameters. Ask us for our full product listing, which includes our comprehensive offering of bioprocessing products along with literature references and other useful information.

Product Name
Mechanism
Bioprocessing Effect
Category
Antioxidant (ROS scavenger)
Increases recombinant protein production:
Reduces glycation and formation of acidic
charge variants
Protein production/
titre
Autophagy inhibitor
(Vacuolar H+ -ATPase inhibitor)
Increases recombinant protein expression
in cells
Protein production/
titre
Promotes proliferation (EP4
receptor activator)
Increases cell specific productivity
Protein production/
titre
Cell cycle arrest (DNA polymerase
inhibitor)
Enhances transfection efficiency
Protein production/
titre
Cofactor (Essential)
Essential for many metabolism pathways
Cell growth and
function
7-alpha Hydroxy-c\
holesterol
Building block (Essential)Improved cell function results in higher
protein expression levels in some cell
cycles
Cell growth and
function
MycophenolicacidFucosylation modulatorRetention of essential post-translational modification on therapeutic proteinTherapeutic
protein integrity
Trichostatin AHDAC inhibitor (Reduces epi-
genetic transcriptional repression)
Increases recombinant protein expressionProtein production/
titre
Brefeldin AIntracellular transport inhibitorModulates protein titre and integrityScaleup and
analysis
Chloroquine
phosphate
Improves transfection; increases
cell specific productivity; fine tunes
glycosylation
Modulates protein titre and integrityScaleup and
analysis

DNA Damage and Repair

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Cancer Cell Metabolism

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Mitochondrial Research

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Stem Cells

 Differentiation

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Stem Cells 

Survival

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Stem Cells Expansion and Maintenance 

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