LRRK2/Dardarin Antibody, Clone N231B/34: HRP
Product Sizes
100 ug
SMC-445D-HRP-100UG
About this Product
- SKU:
- SMC-445D-HRP
- Additional Names:
- Leucine-rich repeat kinase 2 Antibody, RIP7 Antibody, PARK8 Antibody, Dardarin Antibody, ROCO 2 Antibody, RIPK7 Antibody, Leucine-rich repeat serine/threonine-protein kinase 2 Antibody, augmented in rheumatoid arthritis 17 Antibody
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- CE/IVD:
- RUO
- translate.label.attr.clone:
- N231B/34 (Formerly sold as S231B-34)
- Clonality:
- Monoclonal
- Conjugate:
- HRP
- Concentration:
- 1 mg/ml
- Extra Details:
- LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features.
- Host:
- Mouse
- Immunogen:
- Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat. <30% identity with LRRK1.
- Isotype:
- IgG2a
- Purification:
- Protein G Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects >200kDa.
- Storage Conditions:
- See Manual
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Monoclonal Antibody
