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Antibodies

Folate Binding Protein Antibody Peroxidase Conjugated

Product Sizes
25 ul
200-103-148S-25UL
About this Product
SKU:
200-103-148S
Additional Names:
FOLR1|goat anti-Folate Binding Protein Antibody HRP Conjugation, Peroxidase Conjugated goat anti-Folate Binding Protein Antibody, Folate receptor alpha, FR-alpha, Folate receptor 1, Milk folate-binding protein, Folate-binding protein 1, FBP
Application:
ELISA, Immunoprecipitation, Western Blot
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Conjugate:
HRP
Concentration:
1 mg/ml
Extra Details:
Folate-binding protein (FBP) are proteins that bind folate, typically the folate receptors and reduced folate carrier. In cancer research it can be a marker for ovarian cancer. It can be measured to help in tumor classification to aid treatment. FBP is over-expressed (20-80 fold) in more than 90% of ovarian and endometrial cancers, as well as 20-50% of breast, lung, colorectal, and renal cell carcinomas. FBP has very limited tissue distribution and expression in non-malignant tissue, making it a good immunotherapy target.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Goat
Immunogen:
Folate Binding Protein [Bovine Milk]
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Bovine
Shipping Conditions:
Dry Ice
Specificity:
Anti-Folate-binding protein is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Goat Serum as well as purified and partial
Storage Conditions:
-20[o]C diluted. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody