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Assay Kits & ELISAs

Human TIMP-1 ELISA Kit

Product Sizes
1 kit
KOA0312-1KIT
About this Product
SKU:
KOA0312
Additional Names:
C-C chemokine receptor type 5, CC-CKR-5, CCR5, CCR5_HUMAN, CD195, CHEMR13, CLGI, Collagenase inhibitor, Erythroid potentiating activity, Fibroblast collagenase inhibitor, HCI, HIV-1 fusion coreceptor, Human Collagenase Inhibitor, Metalloproteinase inhibitor 1, Metalloproteinase inhibitor 1 precursor, TIMP, TIMP metallopeptidase inhibitor 1, TIMP1 protein1, Tissue inhibitor of metalloproteinases, Tissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor|TIMP1
Application:
ELISA
CE/IVD:
RUO
Extra Details:
The tissue inhibitor of metalloproteinases 1(TIMP1) is also called erythroid-potentiating activity(EPA). The X-linked gene for human TIMP1 is expressed in some but not all inactive X-containing somatic-cell hybrids, suggesting that this gene is either prone to reactivation or variable in its inactivation. Purified EPA specifically stimulates human and murine cells of the erythroid lineage, unlike murine interleukin-3(IL-3) which stimulates precursor cells from all haematopoietic lineages. TIMP1 is thought to play a regulatory role in connective tissues by forming inactive complexes with those metalloproteinases that are normally responsible for connective tissue turnover. The human gene encoding TIMP has been mapped to the X chromosome in the region Xp11.1-p11.4. The standard product used in this kit is natural TIMP-1 with the molecular mass of 22KDa.
Immunogen:
Expression system for standard: NSO; Immunogen sequence: C24-A207
Range:
156 pg/ml - 10000 pg/ml
Reactivities:
Human
Sensitivity:
<5 pg/ml
Shipping Conditions:
Blue Ice
Specificity:
Natural and recombinant human TIMP-1. There is no detectable cross-reactivity with other relevant proteins.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Assay Kits: ELISAs