Canstatin Antibody
Product Sizes
100 ug
600-401-R11-100UG
About this Product
- SKU:
- 600-401-R11
- Additional Names:
- COL4A2|Collagen alpha-2(IV) chain
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins. This antibody is suitable for researchers interested in cancer and stem cell research.
- Formulation:
- 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3
- Host:
- Rabbit
- Immunogen:
- Canstatin affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human Canstatin.
- Isotype:
- IgG
- Physical State:
- Lyophilized
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Ambient
- Specificity:
- Anti-Canstatin antibody is directed against human Canstatin protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on 100% homology for the immunogen sequence. Cross reactivity with Canstatin from other sources has not been determined.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-R11