DISP1 Antibody
Product Sizes
100 ug
600-401-AW0-100UG
About this Product
- SKU:
- 600-401-AW0
- Additional Names:
- DISP1|DISP1 Antibody, DISPA, DISPA, Protein dispatched homolog 1
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- DISP1 is the mammalian homolog of the Drosophila Dispatched segment-polarity gene and a key regulator of the Hedgehog (Hh) signaling pathway during embryonic development. DISP1 is required to move Shh from site of synthesis during embryogenesis; mutations in the gene result in lethality at mid-gestation and prevents specification of ventral cell types in the neural tube. Recent results have shown that DISP1 mediates the basolateral secretion of Shh and regulates growth of mammalian long bones through the control of Ihh.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- Anti-DISP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the N-terminus of human DISP1.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-DISP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of DISP1 are known to exist; this antibody will detect both isoforms. DISP1 antibody is predicted to not cross-react with EMX1.
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-AW0