MIP-3 alpha Biotin Conjugated Antibody
Product Sizes
100 ug
209-306-B51-100UG
About this Product
- SKU:
- 209-306-B51
- Additional Names:
- CCL20|mouse anti-MIP-3 alpha Antibody biotin Conjugated, mouse anti-MIP-3a biotin Conjugated Antibody, MIP-3A Alpha , CCL20, C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1
- Application:
- Western Blot
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 3N2D9
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Concentration:
- 1 mg/ml
- Extra Details:
- MIP-3A Alpha (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3A Alpha inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3A Alpha also possesses antibacterial activity against E.coli and S.aureus. MIP-3A Alpha is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Mouse
- Immunogen:
- Anti-MIP-3A Alpha (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human MIP-3A Alpha produced in E.coli followed by hybridoma development.
- Isotype:
- IgG
- Physical State:
- Lyophilized
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- This product was purified from mouse ascites by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human MIP-3A Alpha protein. A BLAST analysis was used to suggest cross-reactivity with MIP-3A Alpha from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with MIP-3A Alpha from other sources has not
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=209-306-B51
