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Antibodies

CD80 Phycoerythrin Antibody

Product Sizes
100 ug
200-B08-N89-100UG
About this Product
SKU:
200-B08-N89
Additional Names:
Cd80|T-lymphocyte activation antigen CD80, Activation B7-1 antigen, B7, CD80, Cd80
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Buffer:
0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
translate.label.attr.clone:
16-10A1
Clonality:
Monoclonal
Conjugate:
R-PE
Concentration:
0.2 mg/ml
Extra Details:
Anti-CD80 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
Formulation:
0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Hamster
Immunogen:
Anti-CD80 Antibody (Monoclonal) was produced by repeated immunizations with CD80 antigen.
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
Phycoerythrin conjugated CD80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD80. Cross reactivity with CD80 from other sources has not been tested. Anti-CD80 is conjugated with PE under optimal conditions and the solution is free of unconjugated PE.
Storage Conditions:
2-8[o]C unopened. Protect from light.
Supplier:
Rockland Inc
Type:
Antibody: Monoclonal Antibody
Flow Cytometry of anti-CD80 Phycoerythrin Conjugated Monoclonal Antibody. Cells: C57BL/6 mouse splenocytes. Stimulation: LPS for 3 days (right panel). Antibody: (Dotted Line) PE Armenian hamster IgG isotype control; (Solid Line) Phycoerythrin Anti-CD80 antibody using 0.125ug.