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Antibodies

Caspr Antibody

Product Sizes
100 ug
200-301-F03-100UG
About this Product
SKU:
200-301-F03
Additional Names:
CASPR1, CNTP1, Contactin associated protein 1, NCP1, Paranodin, Neurexin 4, p190, Caspr, NRXN4, Neurexin IV, Neurexin-4|Cntnap1
Application:
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
translate.label.attr.clone:
S65-35
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex. Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Mouse
Immunogen:
CASPR Antibody was produced in mice by repeated immunizations with a fusion protein of rat CASPR.
Isotype:
IgG1
Physical State:
Liquid
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Dry Ice
Specificity:
Anti-CASPR Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CASPR from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with CASPR from other sources has not been determined. Scaffolds research.
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Monoclonal Antibody