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Proteins and Peptides

SCF

Product Sizes
2ug
£116.47
M30-010S-2UG
About this Product
SKU:
M30-010S
Additional Names:
Kitl; Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; Kitlg; contrasted; mSCF
Buffer:
50 mM aceetic acid
Extra Details:
TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.
Formulation:
lyophilized
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech