GPR15L
Product Sizes
5ug
£178.82
100-444S-5UG
About this Product
- SKU:
- 100-444S
- Additional Names:
- Antimicrobial peptide-57; AP-57; Colon-derived SUSD2 binding factor; CSBF; UNQ1833/PRO3446
- translate.label.attr.clone:
- (#1L34)
- Extra Details:
- IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues, and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF-induced differentiation of skeletal myoblasts, without affecting IGF-induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF-independent mechanism, which causes a delay in the G1 phase of the cell cycle and increased apoptosis. Recombinant Human IGF-BP7 is a 26.4 kDa protein consisting of 256 amino acid residues.
- Formulation:
- lyophilized
- Host:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech