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Proteins and Peptides

FGF-5

Product Sizes
10ug
£178.82
100-018S-10UG
About this Product
SKU:
100-018S
Additional Names:
FGF5; HBGF-5; Smag-82
Buffer:
5 mM Tris, pH 7.2 + 50 mM NaCl
Extra Details:
GDF-15 belongs to the TGF-β cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in placenta and to a much lesser extent in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest a role for GDF-15 in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers. Human GDF-15/MIC-1 is a disulfide linked homodimeric protein consisting of two 114 amino-acid polypeptide chains.
Formulation:
lyophilized
Host:
E. coli
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech