KI67 Monoclonal Antibody
Product Sizes
KI67 Monoclonal Antibody
£512.00
RD85485A-120UL
About this Product
- SKU:
- RD85485A-120UL
- Additional Names:
- Antigen identified by monoclonal Ki 67,Antigen identified by monoclonal Ki-67,Antigen KI-67,Antigen KI67,Antigen Ki67,KI67,KIA,Marker of proliferation Ki-67,MIB 1,MIB,MKI67,PPP1R105,Proliferation marker protein Ki-67,Proliferation related Ki 67 antigen,Protein phosphatase 1 regulatory subunit 105,RP11-380J17.2
- Application:
- IHC-Paraffin, Immunofluorescence, Immunohistochemistry
- Buffer:
- PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
- Clone:
- Clone:8K5
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
- Gene Details:
- MKI67
- Host:
- Mouse
- Immunogen:
- Synthetic Peptide
- Isotype:
- IgG
- Protein Details:
- P46013
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 120 ul
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Synonyms:
- antigen identified by monoclonal antibody Ki-67;antigen Ki67;KIA;MIB-;MIB-1;Molecular Immunology Borstel antibody 1;PPP1R105;proliferation marker protein Ki-67;proliferation-related Ki-67 antigen;protein phosphatase 1, regulatory subunit 105
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/19273/KI67_Monoclonal_Antibody/