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Antibodies

GLP1R Polyclonal Antibody

Product Sizes
GLP1R Polyclonal Antibody
£512.00
RD85172A-120UL
Academic Pricing
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About this Product
SKU:
RD85172A-120UL
Additional Names:
GLP1R,GLP-1,GLP-1-R,GLP-1R
Application:
Western Blot
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
Gene Details:
GLP1R
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human GLP1R (NP_002053.3).
Isotype:
IgG
Protein Details:
P43220
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Size:
120 ul
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody
Synonyms:
GLP-1;GLP1 receptor;GLP-1 receptor;GLP-1R;GLP-1-R;glucagon-like peptide 1 receptor;seven transmembrane helix receptor