53BP1 Polyclonal Antibody
Product Sizes
53BP1 Polyclonal Antibody
£512.00
RD83484A-120UL
About this Product
- SKU:
- RD83484A-120UL
- Additional Names:
- TP53BP1,53BP1,TDRD30,TP53,p202,p53BP1
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Gene Details:
- TP53BP1
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human 53BP1 (NP_001135452.1).
- Isotype:
- IgG
- Protein Details:
- Q12888
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 120 ul
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Synonyms:
- 53BP1;p202;p53-binding protein 1;p53BP1;TDRD30;TP53-binding protein 1;tumor protein 53-binding protein, 1;tumor suppressor p53-binding protein 1
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/24291/53BP1_Polyclonal_Antibody/