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Antibodies

(KO Validated) LITAF Polyclonal Antibody

Product Sizes
(KO Validated) LITAF Polyclonal Antibody
£588.00
RD83324A-120UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
RD83324A-120UL
Additional Names:
LITAF,PIG7,SIMPLE,TP53I7
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
Gene Details:
LITAF
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human LITAF (NP_004853.2).
Isotype:
IgG
Protein Details:
Q99732
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Size:
120 ul
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody
Synonyms:
lipopolysaccharide-induced TNF-alpha factor;lipopolysaccharide-induced tumor necrosis factor-alpha factor;LPS-induced TNF-alpha factor;p53-induced gene 7 protein;PIG7;SIMPLE;small integral membrane protein of lysosome/late endosome;TP53I7;tumor protein p53 inducible protein 7