(KO Validated) APEX1 Polyclonal Antibody
Product Sizes
(KO Validated) APEX1 Polyclonal Antibody
£588.00
RD82710A-120UL
About this Product
- SKU:
- RD82710A-120UL
- Additional Names:
- APEX1,APE,APE1,APEN,APEX,APX,HAP1,REF1
- Application:
- Immunofluorescence, Western Blot
- Buffer:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
- Gene Details:
- APEX1
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human APEX1 (NP_542380.1).
- Isotype:
- IgG
- Protein Details:
- P27695
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 120 ul
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Synonyms:
- AP endonuclease class I;AP lyase;APE;APE1;APEN;APEX;APEX nuclease;APEX nuclease (multifunctional DNA repair enzyme) 1;apurinic/apyrimidinic (abasic) endonuclease;apurinic-apyrimidinic endonuclease 1;APX;deoxyribonuclease (apurinic or apyrimidinic);DNA-(apurinic or apyrimidinic site) endonuclease;DNA-(apurinic or apyrimidinic site) lyase;HAP1;protein REF-1;redox factor-1;REF1;REF-1
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/23517/KO_Validated_APEX1_Polyclonal_Antibody/