(KO Validated) NCOA2 Polyclonal Antibody
Product Sizes
(KO Validated) NCOA2 Polyclonal Antibody
£874.00
RD80311A-200UL
About this Product
- SKU:
- RD80311A-200UL
- Additional Names:
- NCOA2,GRIP1,KAT13C,NCoA-2,SRC2,TIF2,bHLHe75
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants.
- Gene Details:
- NCOA2
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human NCOA2 (NP_006531.1).
- Isotype:
- IgG
- Protein Details:
- Q15596
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 200 ul
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Synonyms:
- bHLHe75;class E basic helix-loop-helix protein 75;glucocorticoid receptor-interacting protein-1;GRIP1;KAT13C;NCoA-2;nuclear receptor coactivator 2;p160 steroid receptor coactivator 2;SRC2;TIF2;transcriptional intermediary factor 2
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/21121/KO_Validated_NCOA2_Polyclonal_Antibody/